Multiple Sclerosis

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Multiple sclerosis (MS) is a chronic disease that affects the central nervous system. MS is thought to be an autoimmune disease. In MS, the body’s immune system produces cells and proteins (antibodies) that attack myelin, a fatty substance that protects nerve fibers. The cause of MS is unknown. It is not an inherited disease, but it appears that genetic factors play a role in making some people more susceptible to developing it.

  • - MS affects significantly more women than men. Most patients first begin to have symptoms between the ages of 20 - 50.
  • - The course of MS varies among patients. The disease may be mild, moderate, or severe. Most patients have the relapsing-remitting form of MS in which flare-ups (also called relapses or exacerbations) of symptoms are followed by periods of remission.
  • - Symptoms of MS include fatigue; vision problems; difficulty walking; muscle weakness, stiffness, and spasms; bladder and bowel problems. Not all patients experience all symptoms.

Treatment

  • - Interferon beta-1b (Betaseron, Extavia).
  • - Interferon beta-1a (Avonex).
  • - Interferon beta-1a (Rebif).
  • - Glatiramer acetate (Copaxone).
  • - Natalizumab (Tysabri).
  • - Mitoxantrone (Novantrone).