GBS - Plasmapharesis / IVIG Inj



Guillain-Barre syndrome is a serious disorder that occurs when the body's defense (immune) system mistakenly attacks part of the nervous system. This leads to nerve inflammation that causes muscle weakness.


Symptoms of Guillain-Barre can get worse very quickly. It may take only a few hours to reach the most severe symptoms, but weakness that increases over several days is also common.

Muscle weakness or the loss of muscle function (paralysis) affects both sides of the body. In most cases, the muscle weakness starts in the legs and then spreads to the arms. This is called ascending paralysis.

Patients may notice tingling, foot or hand pain, and clumsiness. If the inflammation affects the nerves to the diaphragm and chest and there is weakness in those muscles, the person may need breathing assistance.

Typical symptoms include :

  • - Loss of reflexes in the arms and legs.
  • - Low blood pressure or poor blood pressure control.
  • - Muscle weakness or loss of muscle function (paralysis).
  • - In mild cases, there may be weakness instead of paralysis.
  • - May begin in the arms and legs at the same time.
  • - May get worse over 24 to 72 hours.
  • - May occur in the nerves of the head only.
  • - May start in the arms and move downward.
  • - May start in the feet and legs and move up to the arms and head.
  • - Numbness.
  • - Sensation changes.
  • - Tenderness or muscle pain (may be a cramp-like pain).
  • - Uncoordinated movement.